<p>Prolonged low-dose infusion for gemcitabine: a systematic review</p>

Low-dose Gemcitabine and Carboplatin as a Good Palliation for Local Symptoms in Advanced Transitional Cell Carcinoma of Bladder

Meta-analysis of gemcitabine in brief versus prolonged low-dose infusion for advanced non-small cell lung cancer

OBJECTIVE To evaluate the efficacy and safety of gemcitabine (GEM) at 30 min standard-dose infusion (30 min-SDI) compared with prolonged low-dose infusion (P-LDI) in patients with advanced non-small-cell lung cancer (NSCLC). METHODS Electronic databases including Pubmed, EMbase, Cochrane Library, CNKI, CBM, and VIP were searched using keywords "GEM", "P-LDI", and "NSCLC". Review Manager 5.3 w...

Low-dose clonidine infusion during labour.

In this study, we have compared two different doses of clonidine (bolus of 25 micrograms and infusion of 19 micrograms h-1; bolus of 50 micrograms and infusion of 37 micrograms h-1, both added to 0.03% bupivacaine) with a control group of 0.03% bupivacaine alone. The study was performed in a randomized, double-blind manner, and a total of 45 patients were studied. Both clonidine regimens result...

low-dose gemcitabine and carboplatin as a good palliation for local symptoms in advanced transitional cell carcinoma of bladder

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High dose of bolus iron vs. low dose of weekly infusion: bolusing high dose, a recipe for iron toxicity?

Sir, We read with interest the article by Kosch et al. w1x comparing the i.v. infusion of iron sucrose with iron gluconate in patients on haemodialysis. Although this study provides some direct comparative analysis between two forms of parenteral iron compounds, the implication that iron sucrose being a monthly bolus dose might be better than the more frequently, Nephrol Dial Transplant (2002) ...